SCHEMBL21155199

SCHEMBL21155199

O=S(=O)(c1ccc(O)cc1)c1ccc(Oc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
LTA4H P09960 1/20 0.57
NR1H2 P55055 1/20 0.57
BAX Q07812 1/20 0.57
GAA P10253 1/20 0.56
PKM P14618 1/20 0.56
UQCRB P14927 1/20 0.53
BCL2L1 Q07817 4/20 0.52
MCL1 Q07820 3/20 0.52
MMP3 P08254 3/20 0.52
ELANE P08246 1/20 0.49
SOS1 Q07889 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
ADAMTS4 O75173 1/20 0.46
MMP2 P08253 2/20 0.46
MMP9 P14780 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10052249 0.97 HTT (0.57) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL24445992 0.97 HTT (0.57) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL24445613 0.97 HTT (0.57) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL14463488 0.93 PKM (0.63) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL12780829 0.93 PKM (0.63) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL23430824 0.91 LTA4H (0.69) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL24445611 0.91 LTA4H (0.63) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL7938159 0.91 LTA4H (0.63) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL24445604 0.91 LTA4H (0.63) HTTSMN1; SMN2LTA4HNR1H2BAX
SCHEMBL416827 0.91 LTA4H (0.69) HTTSMN1; SMN2LTA4HNR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321499-A1 GOLF CLUB HEAD TAYLOR MADE GOLF COMPANY, INC. (US) 2023-10-12 US disclosed
US-20220032136-A1 GOLF CLUB HEAD JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2022-02-03 US disclosed
US-20190209973-A1 MULTILAYER HOLLOW FIBRE MEMBRANES BASF SE (DE) 2019-07-11 US disclosed