Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | TOP2A | P11388 | 3/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24266526 | 0.99 | FDPS (0.55) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL24080309 | 0.93 | FDPS (0.59) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL21155668 | 0.91 | NFE2L2 (0.62) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL20906899 | 0.90 | FDPS (0.62) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL21155988 | 0.90 | FDPS (0.54) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL19415798 | 0.89 | NFE2L2 (0.61) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL18570142 | 0.89 | FDPS (0.61) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL18569880 | 0.87 | FDPS (0.58) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL21156513 | 0.86 | FDPS (0.43) | FDPSAPPTOP2ANFE2L2KDM4E | |
| SCHEMBL18570024 | 0.86 | FDPS (0.59) | FDPSAPPNFE2L2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135110-B1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | TRIOPTOTEC GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |