Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344426 | 0.79 | EPHX2 (0.58) | EPHX2KDM1AMAOBKMT2AMAPK10 | |
| SCHEMBL24981627 | 0.77 | EPHX2 (0.53) | EPHX2KDM1AMAOBKMT2AMAPK10 | |
| SCHEMBL6422878 | 0.76 | EPHX2 (0.41) | EPHX2KMT2AMEN1NPC1MAPK10 | |
| SCHEMBL3484895 | 0.76 | EPHX2 (0.49) | EPHX2KDM1AMAOBMAPK10IDO1 | |
| SCHEMBL3484898 | 0.76 | EPHX2 (0.49) | EPHX2KDM1AMAOBMAPK10IDO1 | |
| SCHEMBL23188801 | 0.74 | EPHX2 (0.44) | EPHX2KDM1AMAOBKMT2AMAPK10 | |
| SCHEMBL19370955 | 0.69 | GAA (0.47) | EPHX2KDM1AMAOBBRD4CREBBP | |
| SCHEMBL6068960 | 0.68 | EPHX2 (0.45) | EPHX2KDM1AMAOBKMT2ANFKB1 | |
| SCHEMBL6068965 | 0.68 | EPHX2 (0.45) | EPHX2KDM1AMAOBKMT2ANFKB1 | |
| SCHEMBL7819752 | 0.68 | EPHX2 (0.47) | EPHX2KDM1AMAOBKMT2AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |