SCHEMBL21156624

SCHEMBL21156624

CC(C)(C)c1cc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)c2c(c1)c1cc(C(C)(C)C)cc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)c1n2-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.39
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
LMNA P02545 2/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
WHR1 P49842 1/20 0.34
RXRA P19793 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21157080 0.96 ABCG2 (0.37) ABCG2MEN1KMT2ALMNARAB9A
SCHEMBL21157912 0.95 ABCG2 (0.36) ABCG2LMNATP53MAPTRXRA
SCHEMBL21157802 0.92 ABCG2 (0.40) ABCG2MEN1KMT2ALMNARAB9A
SCHEMBL21157816 0.90 TP53 (0.38) ABCG2MEN1KMT2ALMNARAB9A
SCHEMBL21157804 0.90 TP53 (0.38) ABCG2MEN1KMT2ALMNARAB9A
SCHEMBL21157224 0.88 ABCG2 (0.40) ABCG2MEN1KMT2ALMNARAB9A
SCHEMBL21157225 0.88 ABCG2 (0.40) ABCG2MEN1KMT2ARAB9ATP53
SCHEMBL21157812 0.88 ABCG2 (0.40) ABCG2MEN1KMT2ALMNARAB9A
SCHEMBL21156619 0.88 KIF11 (0.39) KMT2ALMNARAB9ANPC1MAPT
SCHEMBL21157849 0.85 ABCG2 (0.38) ABCG2MEN1KMT2ARAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE TEAD2, TEAD3, TEAD1 ABCG2 283/4885MEN1 4137/4885KMT2A 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.