Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.54 |
| ▸ | XDH | P47989 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | BLVRB | P30043 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867598 | 0.83 | KDM4E (0.67) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL12970049 | 0.83 | RAB9A (0.77) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL892234 | 0.82 | RAB9A (1.00) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL8867920 | 0.81 | RAB9A (0.61) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL28295522 | 0.81 | CDC7 (0.67) | KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL21157454 | 0.81 | RAB9A (0.57) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL289112 | 0.81 | SMN1; SMN2 (0.93) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL2011167 | 0.81 | RAB9A (0.79) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL8867051 | 0.81 | RAB9A (0.79) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL1327631 | 0.80 | SMN1; SMN2 (1.00) | RAB9AKDM4EGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952513-B1 | AZOLE BENZENE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2019-07-10 | — | — | EP | disclosed |