Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957351 | 0.79 | HTR2A (0.64) | HTR2AHTR2C | |
| SCHEMBL2572126 | 0.79 | HTR2A (0.51) | HTR2AHTR2CCA1CA2 | |
| SCHEMBL25566333 | 0.79 | HTR2A (0.48) | HTR2ACYP3A4HTR2C | |
| SCHEMBL9953362 | 0.78 | NPC1 (0.58) | HTR2AHTR2CNPC1 | |
| SCHEMBL168792 | 0.77 | TDO2 (0.43) | HTR2ANPC1KDM4E | |
| SCHEMBL24097713 | 0.77 | HTR2A (0.48) | HTR2ACYP3A4HTR2CCA1CA2 | |
| SCHEMBL4856372 | 0.75 | CYP3A4 (0.38) | HTR2ACYP3A4CA1CA2NPC1 | |
| SCHEMBL24097809 | 0.75 | HTR2A (0.48) | HTR2AHTR2CCA1CA2 | |
| SCHEMBL21157883 | 0.74 | PTGDR2 (0.50) | HTR2ACYP3A4HTR2CKDM4E | |
| SCHEMBL30868519 | 0.74 | HTR2A (0.54) | HTR2APDGFRBPDGFRAHTR2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |