Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL8330626 | 0.91 | ALDH1A1 (0.48) | PTGDR2NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL8785502 | 0.84 | PTGDR2 (0.49) | PTGDR2NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL8785638 | 0.84 | PTGDR2 (0.49) | PTGDR2NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL27811448 | 0.83 | SIGMAR1 (0.49) | ALDH1A1CYP3A4SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL27831702 | 0.82 | HTR2A (0.48) | NOS3NOS1NOS2ALDH1A1SIGMAR1 | |
| SCHEMBL6616630 | 0.79 | PTGDR2 (0.54) | PTGDR2NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL27339809 | 0.79 | PTGDR2 (0.50) | PTGDR2NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL4253290 | 0.78 | ALDH1A1 (0.43) | NOS3NOS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL15718389 | 0.78 | ALDH1A1 (0.50) | NOS3NOS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL20103281 | 0.77 | PTGDR2 (0.52) | PTGDR2NOS3NOS1NOS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |