Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590561 | 0.97 | — | — | |
| SCHEMBL7586949 | 0.83 | HSD17B1 (0.50) | APPESR1ESR2KDM4ENPC1 | |
| SCHEMBL15243106 | 0.83 | APP (0.44) | APPESR1ESR2 | |
| SCHEMBL498630 | 0.81 | DPP4 (0.53) | KDM4ENPC1GLAMAPTRAB9A | |
| SCHEMBL7590473 | 0.79 | RAB9A (0.48) | APPESR1ESR2KDM4ENPC1 | |
| SCHEMBL357574 | 0.78 | — | — | |
| SCHEMBL2592381 | 0.75 | DPP4 (0.53) | APPKDM4EMAPT | |
| SCHEMBL12293440 | 0.65 | — | — | |
| SCHEMBL2855363 | 0.65 | — | — | |
| SCHEMBL19089756 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214581-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214581-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | OCIAD2, OCIAD1, EED | APP 1855/4885ESR1 1176/4885ESR2 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.