Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.58 |
| ▸ | MGAM | O43451 | 10/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 10/20 | 0.58 |
| ▸ | SI | P14410 | 10/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.58 |
| ▸ | F12 | P00748 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193247 | 0.89 | GAA (0.57) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL3944546 | 0.87 | MGAM (0.65) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27397872 | 0.86 | MGAM (0.54) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL9601344 | 0.84 | ASAH1 (0.62) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27972637 | 0.84 | ASAH1 (0.62) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL11490925 | 0.84 | ASAH1 (0.62) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27972795 | 0.84 | ASAH1 (0.62) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL27398405 | 0.84 | F12 (0.50) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL425817 | 0.83 | FAAH (0.69) | — | |
| SCHEMBL459733 | 0.83 | GAA (0.60) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | claimed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | claimed |
| EP-2398760-A1 | ALLOSTERIC BINDING COMPOUNDS | Aarhus Universitet (DK) | 2011-12-28 | — | — | EP | claimed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | claimed |
| US-4187186-A | WEAR, OXIDATION AND CORROSION RESISTANT | MOBIL OIL CORPORATION (US) | 1980-02-05 | — | — | US | claimed |
| WO-2024065582-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE | 宁德新能源科技有限公司 | 2024-04-04 | — | — | WO | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDTJYLLAND (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | REGION MIDT JYLLAND (DK) | 2012-04-19 | — | — | US | disclosed |
| EP-2398760-A1 | ALLOSTERIC BINDING COMPOUNDS | Aarhus Universitet (DK) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010094289-A1 | ALLOSTERIC BINDING COMPOUNDS | AARHUS UNIVERSITET (DK) | 2010-08-26 | — | — | WO | disclosed |
| CN-1735592-A | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | GLAXO GROUP LTD (GB) | 2006-02-15 | — | — | CN | disclosed |
| WO-2001012150-A1 | COSMETIC COMPOSITIONS WITH THERMOCHROMIC COLOR CHANGE SUBSTANCES AND AN AGENT FOR INDUCING A TEMPERATURE CHANGE | UNILEVER PLC (GB) | 2001-02-22 | — | — | WO | disclosed |
| US-4847178-A | Positive photosensitive o-quinone diazide composition with benzotriazole carboxylic acid or alkyl ester | TOKYO OHKA KOGYO CO., LTD. (JP) | 1989-07-11 | — | — | US | disclosed |
| US-4187186-A | WEAR, OXIDATION AND CORROSION RESISTANT | MOBIL OIL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095048-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | GAA 2221/4885MGAM 4382/4885AMY1A 3836/4885 |
| US-20130123326-A1 | ALLOSTERIC BINDING COMPOUNDS | GRIN2C, GRM2, GRIN2B | GAA 2221/4885MGAM 4382/4885AMY1A 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.