SCHEMBL459733

SCHEMBL459733

COC(=O)n1nnc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 10/20 0.60
MGAM O43451 9/20 0.60
AMY1A P0DUB6 9/20 0.60
SI P14410 9/20 0.60
MGAM2 Q2M2H8 9/20 0.60
F12 P00748 7/20 0.60
MIF P14174 1/20 0.60
KMT2A Q03164 3/20 0.58
F2 P00734 2/20 0.58
HPGD P15428 1/20 0.58
SLC9A1 P19634 1/20 0.58
DGAT1 O75907 1/20 0.56
KCNMA1 Q12791 1/20 0.54
ALDH1A1 P00352 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MAPT P10636 1/20 0.54
HTT P42858 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ASAH1 Q13510 1/20 0.52
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2115731 0.83 GAA (0.58) GAAMGAMAMY1ASIMGAM2
SCHEMBL1971916 0.82 GAA (0.54) GAAMGAMAMY1ASIMGAM2
SCHEMBL14639695 0.82 GAA (0.54) GAAMGAMAMY1ASIMGAM2
SCHEMBL535054 0.80 GAA (0.64) GAAMGAMAMY1ASIMGAM2
SCHEMBL3838765 0.80 GAA (0.59) GAAMGAMAMY1ASIMGAM2
SCHEMBL10624555 0.80 GAA (0.53) GAAMGAMAMY1ASIMGAM2
SCHEMBL14193247 0.80 GAA (0.57) GAAMGAMAMY1ASIMGAM2
SCHEMBL706083 0.80 MGAM (0.68) GAAMGAMAMY1ASIMGAM2
SCHEMBL4250719 0.80 GAA (0.68) GAAMGAMAMY1ASIMGAM2
SCHEMBL17875212 0.79 ASAH1 (0.59) GAAMGAMAMY1ASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497490-B2 Millable silicone rubber composition, silicone rubber cured product, and electrically-insulating member for power cable connection SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-16 US claimed
CN-119931782-A Efficient circuit board stripping liquid and preparation method and stripping method thereof 信丰超淦科技有限公司 2025-05-06 CN claimed
CN-114269861-B Mixing type silicone rubber composition, silicone rubber cured product, and electric insulating member for power cable connection 信越化学工业株式会社 2024-03-19 CN claimed
EP-4301816-A1 COATING COMPOSITIONS COMPRISING A POLYSULFIDE CORROSION INHIBITOR PRC-Desoto International, Inc. (US) 2024-01-10 EP claimed
WO-2022187844-A1 COATING COMPOSITIONS COMPRISING A POLYSULFIDE CORROSION INHIBITOR PRC-DESOTO INTERNATIONAL, INC. (US) 2022-09-09 WO claimed
CN-113552781-A Environment-friendly release agent for photosensitive dry film 江西惠美兴科技有限公司 2021-10-26 CN claimed
CN-102037157-B Adhesion promotion of metal to laminate with a multi-functional compound ENTHONE 2014-05-28 CN claimed
CN-102037157-A Adhesion promotion of metal to laminate with a multi-functional compound ENTHONE 2011-04-27 CN claimed
EP-2274460-A1 ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN Enthone, Inc. (US) 2011-01-19 EP claimed
WO-2009117734-A1 ADHESION PROMOTION OF METAL TO LAMINATE WITH A MULTI-FUNCTIONAL COMPOUND HAFTFORDERUNG VON METALL ZU LAMINATEN MIT EINER MULTIFUNKTIONELLEN ENTHONE INC. (US) 2009-09-24 WO claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US claimed
US-5104919-A With curing retardant or flame retardant triazole compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-04-14 US claimed
US-12577412-B2 Corrosion inhibiting coating compositions PRC-DESOTO INTERNATIONAL, INC. (US) 2026-03-17 US disclosed
US-12497490-B2 Millable silicone rubber composition, silicone rubber cured product, and electrically-insulating member for power cable connection SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-16 US disclosed
US-20250377594-A1 RESIST COMPOSITION, METHOD FOR PRODUCING RESIST PATTERN AND METHOD FOR PRODUCING PLATED MOLDED ARTICLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-12-11 US disclosed
US-20250321482-A1 RESIST COMPOSITION, DRY FILM RESIST, METHOD FOR PRODUCING DRY FILM RESIST, METHOD FOR FORMING RESIST PATTERN, AND METHOD FOR PRODUCING PLATED OBJECT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-16 US disclosed
US-4973702-A AMIDES AND ESTERS, UV STABILIZERS FOR PLASTICS AND PHOTOGRAPHIC MATERIALS CIBA-GEIGY CORPORATION (US) 1990-11-27 US disclosed
EP-0388201-A2 Curable silicone composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-09-19 EP disclosed
US-4853471-A 2-(2-Hydroxyphenyl)-benztriazoles, their use as UV-absorbers and their preparation CIBA-GEIGY CORPORATION (US) 1989-08-01 US disclosed
US-4156674-A PLATINUM OR COMPOUND THEREOF, CARBON BLACK AND A TRIAZOLE FOR SELF-EXTINGUISHING CHARACTER, CURING CATALYST AND A SILICON CONTAINING CROSSLINKER TORAY SILICONE COMPANY, LTD. (JP) 1979-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577412-B2 Corrosion inhibiting coating compositions MGMT, MBD2, MECP2 GAA 3475/4885MGAM 1778/4885AMY1A 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.