Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 6/20 | 0.35 |
| ▸ | CHUK | O15111 | 6/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21481187 | 0.95 | IKBKB (0.35) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL21759625 | 0.81 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL21390275 | 0.79 | LIMK1 (0.44) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL20127221 | 0.73 | PDE4D (0.48) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL5477037 | 0.73 | SMN1; SMN2 (0.36) | LIMK1 | |
| SCHEMBL21390270 | 0.72 | CSNK2A1 (0.30) | — | |
| SCHEMBL25760437 | 0.67 | IKBKB (0.40) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL18012098 | 0.66 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL25760406 | 0.65 | IKBKB (0.37) | PDE4APDE4BPDE4CPDE4DIKBKB | |
| SCHEMBL22261460 | 0.64 | KDM4E (0.40) | LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214577-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214577-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE | TEAD2, TEAD3, TEAD1 | PDE4A 2026/4885PDE4B 1315/4885PDE4C 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.