SCHEMBL20127221

SCHEMBL20127221

Cn1cnc2c3ccccc3c3ccccc3c21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 3/20 0.48
PDE4A P27815 2/20 0.48
PDE4B Q07343 2/20 0.48
PDE4C Q08493 2/20 0.48
IKBKB O14920 7/20 0.46
CHUK O15111 7/20 0.46
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
LIMK1 P53667 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39
GABRA4 P48169 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18012098 0.82 PDE4A (0.55) PDE4DPDE4APDE4BPDE4CIKBKB
SCHEMBL21390275 0.79 LIMK1 (0.44) PDE4DPDE4APDE4BPDE4CIKBKB
SCHEMBL3183969 0.77 TLR7 (0.62) PDE4DIKBKBCHUKLMNAPOLB
SCHEMBL21481187 0.77 IKBKB (0.35) PDE4DPDE4APDE4BPDE4CIKBKB
SCHEMBL24499504 0.75 PI4KA (0.39) PDE4DPDE4APDE4BPDE4CIKBKB
SCHEMBL9195572 0.75 SMN1; SMN2 (0.51) PDE4DPDE4APDE4BPDE4CLMNA
SCHEMBL21759625 0.74 PDE4A (0.37) PDE4DPDE4APDE4BPDE4CIKBKB
SCHEMBL11910173 0.73 RAB9A (0.40) PDE4DPDE4APDE4BPDE4CLMNA
SCHEMBL9209628 0.73 ADORA3 (0.48) PDE4DPDE4APDE4BPDE4CLMNA
SCHEMBL9601821 0.73 IKBKB (0.46) PDE4DPDE4APDE4BPDE4CIKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20230320112-A1 POLYMERS, FORMULATIONS, ORGANIC OPTOELECTRONIC DEVICES, AND APPLICATIONS THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-10-05 US disclosed
US-20230320112-A1 POLYMERS, FORMULATIONS, ORGANIC OPTOELECTRONIC DEVICES, AND APPLICATIONS THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-10-05 US disclosed
US-20230272274-A1 FORMULATIONS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-08-31 US disclosed
US-20230272274-A1 FORMULATIONS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-08-31 US disclosed
EP-4231064-A1 COMPOSITIONS AND USE THEREOF IN PHOTOELECTRIC FIELD Zhejiang Brilliant Optoelectronic Technology Co., Ltd. (CN) 2023-08-23 EP disclosed
US-20230250112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-08-10 US disclosed
US-20230255112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD ZHEJIANG BRILLIANT OPTOELECTRONIC TECHNOLOGY CO., LTD. (CN) 2023-08-10 US disclosed
US-11672174-B2 Pyrene-triazine derivative and applications thereof in organic electronic component GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2023-06-06 US disclosed
US-11289654-B2 Polymers containing furanyl crosslinkable groups and uses thereof GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-03-29 US disclosed
US-11239428-B2 Boron-containing organic compound and applications thereof, organic mixture, and organic electronic device GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-02-01 US disclosed
EP-3547385-B1 ORGANIC MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC COMPONENT GUANGZHOU CHINARAY OPTOELECTRONIC MAT LTD (CN) 2020-11-04 EP disclosed
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-10-17 US disclosed
EP-3547384-A1 HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2019-10-02 EP disclosed
EP-3547385-A1 ORGANIC MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC COMPONENT Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2019-10-02 EP disclosed
WO-2018113785-A1 POLYMER CONTAINING FURAN CROSSLINKING GROUP AND USE THEREOF 广州华睿光电材料有限公司 2018-06-28 WO disclosed
WO-2018103746-A1 CARBAZOLE BENZENE FUSED RING DERIVATIVE, POLYMER, MIXTURE, COMPOSITION, ORGANIC ELECTRONIC DEVICE AND PREPARATION METHOD THEREFOR 广州华睿光电材料有限公司 2018-06-14 WO disclosed
US-20180130955-A1 ORGANIC COMPOUND, MIXTURE COMPRISING SAME, COMPOSITE, AND ORGANIC ELECTRONIC COMPONENT GUANGZHOU CHINARAY OPTOELECTRONICS MATERIALS LTD. (CN) 2018-05-10 US disclosed
US-20180130955-A1 ORGANIC COMPOUND, MIXTURE COMPRISING SAME, COMPOSITE, AND ORGANIC ELECTRONIC COMPONENT GUANGZHOU CHINARAY OPTOELECTRONICS MATERIALS LTD. (CN) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130955-A1 ORGANIC COMPOUND, MIXTURE COMPRISING SAME, COMPOSITE, AND ORGANIC ELECTRONIC COMPONENT OCIAD1, OCIAD2, SRD5A1 PDE4D 4490/4885PDE4A 4870/4885PDE4B 4786/4885
US-20230250112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD AOX1, AOC2, OR10J3 PDE4D 4378/4885PDE4A 4336/4885PDE4B 4513/4885
US-20230255112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD OR10J3, AOX1, AOC3 PDE4D 2813/4885PDE4A 2906/4885PDE4B 2650/4885
US-11672174-B2 Pyrene-triazine derivative and applications thereof in organic electronic component TPR, TRPC5, TRPC4 PDE4D 4782/4885PDE4A 4719/4885PDE4B 4728/4885
US-11239428-B2 Boron-containing organic compound and applications thereof, organic mixture, and organic electronic device BCL6B, BCL6, BTD PDE4D 4825/4885PDE4A 4801/4885PDE4B 4647/4885
US-20190319197-A1 ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE PIEZO1, OR10J3, OR51E2 PDE4D 4619/4885PDE4A 4755/4885PDE4B 4664/4885
US-20230363270-A1 ORGANIC COMPOUNDS, ORGANIC MIXTURES AND THE USES THEREOF AOX1, ODC1, OTC PDE4D 4675/4885PDE4A 4775/4885PDE4B 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.