Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21919758 | 0.89 | CA5A (0.36) | CA5ALMNAKMT2AHSD17B1 | |
| SCHEMBL21157993 | 0.83 | CA5A (0.41) | CA5ALMNAKMT2AHSD17B1CREBBP | |
| SCHEMBL15342884 | 0.83 | KMT2A (0.48) | LMNAKMT2AHSD17B1POLBEPHX2 | |
| SCHEMBL10026130 | 0.79 | SERPINE1 (0.50) | CA5ALMNAPOLBSERPINE1L3MBTL1 | |
| SCHEMBL20081133 | 0.76 | ELANE (0.37) | CA5ALMNAKMT2A | |
| SCHEMBL18769406 | 0.75 | CA5A (0.41) | CA5ALMNAKMT2AHSD17B1CREBBP | |
| SCHEMBL669554 | 0.74 | CA5A (0.67) | CA5ALMNAKMT2AHSD17B1PKM | |
| SCHEMBL21124834 | 0.73 | HDAC3 (0.42) | KMT2ANPC1RAB9AHPGD | |
| SCHEMBL22420533 | 0.73 | CYP2C9 (0.49) | KMT2APKMPOLBNR1H4NPC1 | |
| SCHEMBL12508632 | 0.73 | ACHE (0.41) | POLBL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145985-B1 | FUNCTIONALIZED POLYMER PARTICLES FOR USE AS TOUGHENING AGENT | CYTEC IND INC (US) | 2019-07-10 | — | — | EP | disclosed |