Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544984 | 0.96 | DHODH (0.46) | DHODHESR1ESR2ELANEBACE1 | |
| SCHEMBL21158046 | 0.96 | DHODH (0.46) | DHODHESR1ESR2ELANEBACE1 | |
| SCHEMBL23600078 | 0.93 | SMN1; SMN2 (0.44) | DHODHESR1ESR2ELANENPC1 | |
| SCHEMBL21000690 | 0.93 | DHODH (0.48) | DHODHESR1ESR2ELANEBACE1 | |
| SCHEMBL21000582 | 0.93 | DHODH (0.48) | DHODHESR1ESR2ELANEBACE1 | |
| SCHEMBL20413952 | 0.92 | DHODH (0.43) | DHODHESR1ESR2ELANEBACE1 | |
| SCHEMBL19992817 | 0.91 | DHODH (0.47) | DHODHESR1ESR2ELANENPC1 | |
| SCHEMBL24910172 | 0.91 | DHODH (0.47) | DHODHESR1ESR2ELANENPC1 | |
| SCHEMBL21158032 | 0.91 | DHODH (0.47) | DHODHESR1ESR2ELANENPC1 | |
| SCHEMBL21158031 | 0.91 | DHODH (0.44) | DHODHESR1ESR2ELANENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11183640-B2 | Organic electroluminescent device comprising electrontransport layer and electron buffer layer | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. | 2021-11-23 | — | — | US | disclosed |
| US-20190214572-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING ELECTRONTRANSPORT LAYER AND ELECTRON BUFFER LAYER | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11183640-B2 | Organic electroluminescent device comprising electrontransport layer and electron buffer layer | SLC8B1, SLC9A2, SLC9B2 | DHODH 2391/4885ESR1 264/4885ESR2 425/4885 |
| US-20190214572-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING ELECTRONTRANSPORT LAYER AND ELECTRON BUFFER LAYER | SLC8B1, SLC9A2, SLC9B2 | DHODH 2391/4885ESR1 264/4885ESR2 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.