Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20691448 | 1.00 | TYMP (0.46) | TYMPADORA2AADORA2BPRMT6P2RY12 | |
| SCHEMBL23772807 | 1.00 | TYMP (0.46) | TYMPADORA2AADORA2BPRMT6P2RY12 | |
| SCHEMBL31093231 | 0.90 | TYMP (0.49) | TYMPADORA2AADORA2BP2RY12ADORA1 | |
| SCHEMBL13375789 | 0.90 | ADORA1 (0.41) | TYMPADORA2BADORA1 | |
| SCHEMBL21474287 | 0.89 | TYMP (0.46) | TYMPADORA2AADORA2BADORA1PRKAG1 | |
| SCHEMBL13375787 | 0.88 | ADORA3 (0.39) | TYMPADORA2BADORA1 | |
| SCHEMBL28646926 | 0.87 | TYMP (0.46) | TYMPADORA2AADORA2BPRMT6P2RY12 | |
| SCHEMBL13057654 | 0.87 | TYMP (0.51) | TYMPADORA2AADORA2BP2RY12ADORA1 | |
| SCHEMBL18496453 | 0.87 | TYMP (0.51) | TYMPADORA2AADORA2BP2RY12ADORA1 | |
| SCHEMBL18490400 | 0.87 | TYMP (0.46) | TYMPADORA2AADORA2BPRMT6P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250368-A2 | ATXN2 RNA INTERFERENCE AGENTS | ELI LILLY AND COMPANY (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023177972-A1 | SARM1 RNA INTERFERENCE AGENTS | ELI LILLY AND COMPANY (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-3658565-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-11-09 | — | — | EP | disclosed |
| EP-3865576-A1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | Dicerna Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3569711-B1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | DICERNA PHARMACEUTICALS INC (US) | 2021-02-03 | — | — | EP | disclosed |
| EP-3569711-A1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | Dicerna Pharmaceuticals, Inc. (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-3234132-B1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | DICERNA PHARMACEUTICALS INC (US) | 2019-07-10 | — | — | EP | disclosed |