Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800827 | 0.86 | HCAR2 (0.58) | LMNAHCAR2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL9454253 | 0.81 | CA12 (0.46) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL20888388 | 0.80 | NPC1 (0.44) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL31124057 | 0.79 | MAPT (0.49) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL18506410 | 0.79 | CA12 (0.41) | LMNAPOLBL3MBTL1ALDH1A1CA12 | |
| SCHEMBL368680 | 0.79 | ALDH1A1 (0.43) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL2184554 | 0.79 | GAA (0.44) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL14770789 | 0.79 | RAB9A (0.45) | LMNAL3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL12852737 | 0.78 | NPC1 (0.45) | LMNAPOLBALDH1A1CA12CA1 | |
| SCHEMBL8118231 | 0.78 | CHRNA4 (0.45) | LMNAPOLBL3MBTL1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |