Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 6/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138230 | 0.99 | ALDH1A1 (0.42) | MEN1ALDH1A1HPGDKMT2AHTT | |
| SCHEMBL21057262 | 0.99 | ALDH1A1 (0.42) | MEN1ALDH1A1HPGDKMT2AHTT | |
| SCHEMBL21138133 | 0.99 | ALDH1A1 (0.42) | MEN1ALDH1A1HPGDKMT2AHTT | |
| SCHEMBL21138246 | 0.83 | CHRM4 (0.36) | MEN1ALDH1A1HPGDKMT2AHTT | |
| SCHEMBL21138571 | 0.83 | CHRM4 (0.36) | MEN1ALDH1A1HPGDKMT2AHTT | |
| SCHEMBL19917131 | 0.82 | NR1I2 (0.37) | MEN1ALDH1A1HPGDKMT2AADORA3 | |
| SCHEMBL21138141 | 0.82 | NR1I2 (0.37) | ADORA3PBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL21057266 | 0.82 | ADORA3 (0.38) | HTTNPC1LRRK2ADORA3PBRM1 | |
| SCHEMBL21057321 | 0.82 | ADORA3 (0.38) | ADORA3AHCY | |
| SCHEMBL21138471 | 0.81 | ADORA3 (0.40) | ALDH1A1HPGDLRRK2ADORA3AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |