Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 14/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21057298 | 1.00 | ADORA3 (0.46) | ADORA3FGFR2TNK2IGF1RFGFR1 | |
| SCHEMBL19917164 | 1.00 | ADORA3 (0.46) | ADORA3FGFR2TNK2IGF1RFGFR1 | |
| SCHEMBL21057338 | 1.00 | ADORA3 (0.46) | ADORA3FGFR2TNK2IGF1RFGFR1 | |
| SCHEMBL21057513 | 0.88 | ADORA3 (0.51) | ADORA3TNK2 | |
| SCHEMBL21138747 | 0.87 | ADORA3 (0.53) | ADORA3FGFR2TNK2IGF1RFGFR1 | |
| SCHEMBL21057446 | 0.85 | HSD11B1 (0.37) | ADORA3 | |
| SCHEMBL19917049 | 0.85 | HSD11B1 (0.37) | ADORA3 | |
| SCHEMBL21138169 | 0.84 | ADORA3 (0.53) | ADORA3FGFR2TNK2IGF1R | |
| SCHEMBL21057258 | 0.83 | ADORA3 (0.50) | ADORA3FGFR2TNK2IGF1RFGFR1 | |
| SCHEMBL21057256 | 0.83 | ADORA3 (0.50) | ADORA3FGFR2TNK2IGF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |