SCHEMBL21160163

SCHEMBL21160163

Cn1nccc1-c1ccc(-c2ccc3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PORCN Q9H237 1/20 0.43
LMNA P02545 1/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ABL1 P00519 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP19A1 P11511 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
PIK3CD O00329 1/20 0.39
PIK3CA P42336 1/20 0.39
PIK3CB P42338 1/20 0.39
PI4KA P42356 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14938282 0.82 PORCN (0.55) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL23633611 0.80 ESR1 (0.59) ALDH1A1KDM4ESMN1; SMN2LMNAESR1
SCHEMBL21188130 0.80 ESR1 (0.59) ALDH1A1KDM4ESMN1; SMN2LMNAESR1
SCHEMBL23633506 0.80 ESR1 (0.59) ALDH1A1KDM4ESMN1; SMN2LMNAESR1
SCHEMBL21188129 0.80 ESR1 (0.59) ALDH1A1KDM4ESMN1; SMN2LMNAESR1
SCHEMBL21188134 0.80 ESR1 (0.59) ALDH1A1KDM4ESMN1; SMN2LMNAESR1
SCHEMBL14938125 0.79 MAPK9 (0.58) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL26154474 0.78 ESR1 (0.57) ALDH1A1KDM4ESMN1; SMN2LMNAESR1
SCHEMBL16785867 0.78 ESR1 (0.55) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL15850715 0.78 ESR1 (0.61) ALDH1A1KDM4ESMN1; SMN2LMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498804-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-06-03 EP disclosed
EP-3498804-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2019-06-19 EP disclosed