Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160859 | 1.00 | ALDH1A1 (0.38) | ALDH1A1BCHEMAPT | |
| SCHEMBL21159683 | 1.00 | ALDH1A1 (0.38) | ALDH1A1BCHEMAPT | |
| SCHEMBL21160985 | 1.00 | ALDH1A1 (0.38) | ALDH1A1BCHEMAPT | |
| SCHEMBL21160902 | 1.00 | ALDH1A1 (0.38) | ALDH1A1BCHEMAPT | |
| SCHEMBL18324671 | 0.91 | ALDH1A1 (0.33) | ALDH1A1BCHE | |
| SCHEMBL21097547 | 0.91 | ALDH1A1 (0.33) | ALDH1A1BCHE | |
| SCHEMBL12572570 | 0.91 | ALDH1A1 (0.33) | ALDH1A1BCHE | |
| SCHEMBL25097621 | 0.87 | THRB (0.52) | ALDH1A1BCHEMAPT | |
| SCHEMBL21160903 | 0.87 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL21160798 | 0.87 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186678-B2 | Radical cascade-enabled synthesis of precision polymers with complex main-chain structures | TRUSTEES OF BOSTON COLLEGE (US) | 2021-11-30 | — | — | US | disclosed |
| US-20200216610-A1 | RADICAL CASCADE-ENABLED SYNTHESIS OF PRECISION POLYMERS WITH COMPLEX MAIN-CHAIN STRUCTURES | TRUSTEES OF BOSTON COLLEGE (US) | 2020-07-09 | — | — | US | disclosed |
| US-10689391-B2 | Isoxazole analogs as FXR agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190194216-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194216-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | SLC10A1, NR1H4, GPBAR1 | ALDH1A1 1706/4885BCHE 2101/4885MAPT 3955/4885 |
| US-10689391-B2 | Isoxazole analogs as FXR agonists and methods of use thereof | SLC10A1, NR1H4, GPBAR1 | ALDH1A1 1706/4885BCHE 2101/4885MAPT 3955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.