Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21163920 | 1.00 | OPRM1 (0.35) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL21370481 | 1.00 | OPRM1 (0.35) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL20676135 | 1.00 | OPRM1 (0.35) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL18559567 | 1.00 | OPRM1 (0.35) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL19852249 | 0.97 | OPRM1 (0.34) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL18559603 | 0.90 | TSHR (0.34) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL21370269 | 0.90 | TSHR (0.34) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL20676271 | 0.88 | OPRM1 (0.33) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL24777653 | 0.88 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL24777893 | 0.88 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329280-B2 | Urea derivatives and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329280-B2 | Urea derivatives and uses thereof | UACA, RB1, FLT1 | OPRM1 3571/4885OPRD1 3394/4885OPRK1 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.