Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292263 | 0.80 | KDM4E (0.33) | — | |
| SCHEMBL12131114 | 0.74 | LMNA (0.32) | LMNA | |
| SCHEMBL3686517 | 0.72 | NQO1 (0.40) | LMNA | |
| SCHEMBL8800795 | 0.71 | NQO1 (0.35) | — | |
| SCHEMBL27488484 | 0.70 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL28351236 | 0.68 | MAPT (0.31) | — | |
| SCHEMBL11800952 | 0.67 | — | — | |
| SCHEMBL10062276 | 0.67 | GAA (0.30) | — | |
| SCHEMBL7121422 | 0.65 | — | — | |
| SCHEMBL21119049 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505519-A1 | PYRIDINAMINE-SUBSTITUTED HETEROTRICYCLO COMPOUNDS, PREPARATION THEREOF, AND USE IN MEDICINES | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2019-07-03 | — | — | EP | disclosed |