⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122001 | 0.88 | TSHR (0.41) | — | |
| SCHEMBL21787200 | 0.87 | ACHE (0.41) | — | |
| SCHEMBL21570869 | 0.84 | TSHR (0.48) | — | |
| SCHEMBL2056773 | 0.82 | TSHR (0.52) | — | |
| SCHEMBL2056762 | 0.82 | TSHR (0.52) | — | |
| SCHEMBL3686781 | 0.80 | — | — | |
| SCHEMBL12975855 | 0.78 | TSHR (0.37) | — | |
| SCHEMBL14744031 | 0.77 | — | — | |
| SCHEMBL1416001 | 0.77 | — | — | |
| SCHEMBL5924841 | 0.77 | HPGD (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601723-B1 | DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE (US) | 2018-10-31 | — | — | EP | claimed |
| US-8158695-B2 | Forming clear, wettable silicone hydrogel articles without surface treatments | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-04-17 | — | — | US | claimed |
| US-20100280146-A1 | Forming clear, wettable silicone hydrogel articles without surface treatments | JOHNSON & JOHNSON VISION CARE, INC. | 2010-11-04 | — | — | US | claimed |
| EP-1601723-A4 | DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHSON & JOHNSON VISION CARE I (US) | 2007-06-20 | — | — | EP | claimed |
| EP-1601723-A2 | DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | J & J Vision Care, Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| WO-2004081105-A2 | DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JONHSON AND JOHNSON VISION CARE, INC. (US) | 2004-09-23 | — | — | WO | claimed |
| US-6166236-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 2000-12-26 | — | — | US | claimed |
| EP-0757033-B1 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | claimed |
| US-5610252-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1997-03-11 | — | — | US | claimed |
| EP-0757033-A2 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB INCORPORATED (US) | 1997-02-05 | — | — | EP | claimed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | claimed |
| JP-3072506-A | — | — | None | — | — | JP | disclosed |
| WO-2024246822-A1 | METHOD FOR MAKING EMBEDDED SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-12-05 | — | — | WO | disclosed |
| CN-106459308-B | Silicone acrylamide copolymers | 庄臣及庄臣视力保护公司 | 2019-11-15 | — | — | CN | disclosed |
| CN-106459308-A | Silicone acrylamide copolymers | 庄臣及庄臣视力保护公司 | 2017-02-22 | — | — | CN | disclosed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | disclosed |
| US-5070215-A | Gas permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| JP-H0372506-A | NEW VINYL CARBONATE AND VINYL CARBAMATE CONTACT LENS MATERIAL MONOMER | BAUSCH & LOMB INC | 1991-03-27 | — | — | JP | disclosed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | disclosed |