Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122001 | 0.89 | TSHR (0.41) | TSHRACHEALDH1A1TP53HIF1A | |
| SCHEMBL2056773 | 0.83 | TSHR (0.52) | TSHRACHEALDH1A1TP53HIF1A | |
| SCHEMBL3686781 | 0.81 | — | — | |
| SCHEMBL21570869 | 0.80 | TSHR (0.48) | TSHRACHEALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27803239 | 0.79 | KDM4E (0.40) | TSHRACHEALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL640238 | 0.79 | THRB (0.52) | TSHRACHEALDH1A1TP53HIF1A | |
| SCHEMBL2056762 | 0.78 | TSHR (0.52) | TSHRACHEALDH1A1HPGDEPHX1 | |
| SCHEMBL2116165 | 0.78 | — | — | |
| SCHEMBL5924841 | 0.78 | HPGD (0.57) | TSHRACHEALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL21716613 | 0.76 | TDP1 (0.45) | TSHRALDH1A1HSD17B10CHRNB2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104380148-B | The silicone hydrogel lenses for the barrier ultraviolet light polymerizeing completely | 博士伦公司 | 2018-09-28 | — | — | CN | disclosed |
| EP-2856218-A1 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | Bausch & Lomb Incorporated (US) | 2015-04-08 | — | — | EP | disclosed |
| CN-104380148-A | Fully polymerized UV blocking silicone hydrogel lens | BAUSCH & LOMB | 2015-02-25 | — | — | CN | disclosed |
| WO-2013177008-A1 | FULLY POLYMERIZED UV BLOCKING SILICONE HYDROGEL LENS | BAUSCH & LOMB INCORPORATED (US) | 2013-11-28 | — | — | WO | disclosed |
| US-20100315588-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |