Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116282 | 0.88 | PTGER4 (0.50) | PTGER4FDPSALDH1A1MAPTKDM4E | |
| SCHEMBL2116806 | 0.85 | PTGER4 (0.45) | PTGER4FDPSALDH1A1HSD17B10MAPT | |
| SCHEMBL4819927 | 0.84 | ALDH1A1 (0.46) | PTGER4NQO2ALDH1A1CFTRHSD17B10 | |
| SCHEMBL2119160 | 0.83 | KDM4E (0.54) | FDPSALDH1A1HSD17B10PIM1KDM4E | |
| SCHEMBL2115826 | 0.83 | PTGER4 (0.46) | PTGER4FDPSPIM1KDM4EHDAC3 | |
| SCHEMBL2116608 | 0.78 | PTGER4 (0.42) | PTGER4FDPSALDH1A1HSD17B10KDM4E | |
| SCHEMBL9907327 | 0.78 | PDCD1 (0.45) | PTGER4ALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL27822119 | 0.77 | GSK3B (0.39) | FDPSALDH1A1HSD17B10MAPTPIM1 | |
| SCHEMBL8676081 | 0.76 | ALDH1A1 (0.44) | PTGER4FDPSNQO2ALDH1A1CFTR | |
| SCHEMBL3535547 | 0.75 | ALDH1A1 (0.45) | PTGER4NQO2ALDH1A1CFTRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094958-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094958-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | FDPS, GGPS1, CTPS1 | PTGER4 2253/4885FDPS 1/4885NQO2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.