SCHEMBL21163169

SCHEMBL21163169

CC(C)NS(=O)(=O)Cc1cncc(CS(=O)(=O)NC(C)C)n1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
PIK3CD O00329 2/20 0.30
PIK3CG P48736 2/20 0.30
PIK3CA P42336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22446918 0.81 NPSR1 (0.38) MEN1ALDH1A1HTTKMT2A
SCHEMBL21885988 0.81 ALDH1A1 (0.36) MEN1ALDH1A1KMT2A
SCHEMBL21163177 0.78 ALDH1A1 (0.37) MEN1ALDH1A1HTTKMT2APIK3CD
SCHEMBL21886024 0.74 ALDH1A1 (0.37) MEN1ALDH1A1HTTKMT2A
SCHEMBL18571259 0.73 ALDH1A1 (0.43) ALDH1A1KMT2A
SCHEMBL21163174 0.73 ALDH1A1 (0.34) MEN1ALDH1A1HTTKMT2A
SCHEMBL21162921 0.73 ALDH1A1 (0.37) MEN1ALDH1A1HTTKMT2A
SCHEMBL18571397 0.71 KDM4E (0.44) MEN1ALDH1A1HTTKMT2A
SCHEMBL21886084 0.71 APLNR (0.39) MEN1ALDH1A1KMT2A
SCHEMBL21162922 0.70 ALDH1A1 (0.33) MEN1ALDH1A1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190192497-A1 ANTIBODY-RECRUITING MOLECULES FOR THE TREATMENT OF CANCER KLEO PHARMACEUTICALS, INC. 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190192497-A1 ANTIBODY-RECRUITING MOLECULES FOR THE TREATMENT OF CANCER PLAUR, C3AR1, C5AR1 MEN1 1142/4885ALDH1A1 3673/4885HTT 4302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.