Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085545 | 0.99 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL5017241 | 0.92 | LOX (0.45) | SMN1; SMN2LOXGRIN1GRIN2AGRIA1 | |
| SCHEMBL14360459 | 0.86 | KMT2A (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL23468556 | 0.86 | RAB9A (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL12085679 | 0.82 | ALDH1A1 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL3611347 | 0.82 | TSHR (0.43) | SMN1; SMN2LOXGRIN1GRIN2AGRIN2B | |
| SCHEMBL12951454 | 0.81 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL12085613 | 0.80 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL12085543 | 0.77 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL3547639 | 0.76 | BCL2 (0.45) | HDAC3HDAC1HDAC2HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350178-B2 | Methods and compositions for treatment of demyelinating diseases | PATHOLOGICA LLC (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350178-B2 | Methods and compositions for treatment of demyelinating diseases | PMP22, MAG, GMFG | HDAC3 2307/4885HDAC1 1754/4885HDAC2 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.