Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401738 | 0.82 | MEN1 (0.42) | LPAR1HPGDCNR2MEN1HTT | |
| SCHEMBL2173526 | 0.81 | MAPK1 (0.41) | GSK3BDYRK1ABRD9MAPK14NAMPT | |
| SCHEMBL24255818 | 0.80 | CNR2 (0.53) | GSK3BDYRK1AATRBRD9ITGA4 | |
| SCHEMBL20540427 | 0.80 | CCNC (0.37) | GSK3BDYRK1ALPAR1BRD9ITGA4 | |
| SCHEMBL22322779 | 0.79 | CNR2 (0.40) | GSK3BDYRK1AATRBRD9MAPK14 | |
| SCHEMBL18366036 | 0.79 | GSK3B (0.39) | GSK3BDYRK1AATRBRD9ITGA4 | |
| SCHEMBL21164256 | 0.79 | GSK3B (0.39) | GSK3BDYRK1AATRLPAR1ITGA4 | |
| SCHEMBL23009294 | 0.79 | ATR (0.40) | GSK3BDYRK1AATRBRD9MAPK14 | |
| SCHEMBL20772872 | 0.79 | GSK3B (0.39) | GSK3BDYRK1AATRLPAR1ITGA4 | |
| SCHEMBL22952416 | 0.79 | GSK3B (0.39) | GSK3BDYRK1AATRBRD9ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | SANDOZ AG (CH) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | PAICS, PPOX, DDC | GSK3B 2577/4885DYRK1A 525/4885ATR 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.