Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326365 | 0.90 | POLB (0.57) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL22404737 | 0.88 | CTSS (0.64) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL85543 | 0.88 | CTSS (0.64) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL3355326 | 0.88 | CTSS (0.64) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL2721558 | 0.88 | ACE (0.60) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL1691095 | 0.88 | ACE (0.60) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL29750416 | 0.87 | CTSS (0.60) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL16168814 | 0.85 | SYK (0.48) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL5887477 | 0.84 | CTSS (0.62) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL3439255 | 0.84 | CTSS (0.62) | CTSSCTSLCTSBCTSKACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730913-B1 | Antimicrobial analogues of gramicidin S | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-08-04 | — | — | US | disclosed |
| US-10351602-B1 | Antimicrobial analogues of gramicidin S | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730913-B1 | Antimicrobial analogues of gramicidin S | GMPS, AAAS, GNPDA1 | CTSS 405/4885CTSL 101/4885CTSB 396/4885 |
| US-10351602-B1 | Antimicrobial analogues of gramicidin S | GMPS, AAAS, GNPDA1 | CTSS 405/4885CTSL 101/4885CTSB 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.