Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TACR1 | P25103 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21164375 | 0.90 | CTSS (0.53) | POLBTACR1CTSSCTSKCTSL | |
| SCHEMBL14576685 | 0.80 | CTSS (0.56) | POLBTACR1CTSSCTSKCTSL | |
| SCHEMBL20905929 | 0.80 | CTSS (0.56) | POLBTACR1CTSSCTSKCTSL | |
| SCHEMBL30051055 | 0.80 | CTSS (0.56) | POLBTACR1CTSSCTSKCTSL | |
| SCHEMBL20905733 | 0.79 | PTPN1 (0.55) | TACR1CTSSCTSKCTSLCTSB | |
| SCHEMBL7709696 | 0.79 | PTPN1 (0.55) | TACR1CTSSCTSKCTSLCTSB | |
| SCHEMBL268722 | 0.79 | ACE (0.65) | CTSSCTSKCTSLCTSBJAK2 | |
| SCHEMBL16423 | 0.79 | ACE (0.65) | CTSSCTSKCTSLCTSBJAK2 | |
| SCHEMBL29907894 | 0.79 | ACE (0.65) | CTSSCTSKCTSLCTSBJAK2 | |
| SCHEMBL268723 | 0.79 | ACE (0.65) | CTSSCTSKCTSLCTSBJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738085-B1 | Antimicrobial analogues of Gramicidin S | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738085-B1 | Antimicrobial analogues of Gramicidin S | GMPS, AAAS, GNPDA1 | POLB 510/4885TACR1 3714/4885CTSS 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.