Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | LTK | P29376 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18253303 | 0.91 | PDK2 (0.49) | PDK2ADORA2AADORA1AURKAPARP1 | |
| SCHEMBL18253312 | 0.89 | PDK2 (0.45) | PDK2ADORA2AADORA1AURKAPARP1 | |
| SCHEMBL26551074 | 0.81 | PDK2 (0.43) | PDK2AURKAPARP1CDK5ACVR1 | |
| SCHEMBL646449 | 0.79 | GABRA1 (0.47) | ADORA2AADORA1AURKAPARP1MAP4K4 | |
| SCHEMBL18253315 | 0.79 | ESR1 (0.44) | PDK2PRKACAROCK1MAPT | |
| SCHEMBL19893738 | 0.78 | FEN1 (0.56) | PARP1MAP4K4CSF1RFGFR1LTK | |
| SCHEMBL29539083 | 0.78 | FEN1 (0.56) | PARP1MAP4K4CSF1RFGFR1LTK | |
| SCHEMBL4414582 | 0.76 | PDK2 (0.58) | PDK2MAP4K4CSF1RFGFR1LTK | |
| SCHEMBL12093381 | 0.74 | ADORA2A (0.51) | ADORA2AADORA1AURKAPARP1JAK2 | |
| SCHEMBL17969001 | 0.74 | CDK4 (0.54) | MAP4K4CSF1RFGFR1LTKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10355222-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10355222-B2 | Organic electroluminescent materials and devices | OCIAD1, OCIAD2, OPRD1 | PDK2 349/4885ADORA2A 2517/4885ADORA1 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.