Dipyrithione

Dipyrithione

SCHEMBL21165

[O-][n+]1ccccc1SSc1cccc[n+]1[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
HTT P42858 2/20 1.00
SLC2A1 P11166 1/20 0.56
KDM4E B2RXH2 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
KMT2A Q03164 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
RAB9A P51151 4/20 0.48
ALDH1A1 P00352 6/20 0.42
MAPT P10636 3/20 0.42
NPC1 O15118 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GAA P10253 2/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyrithione SCHEMBL29364114 1.00 LMNA (1.00) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL6034282 0.97 LMNA (0.95) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL10973086 0.97 LMNA (0.95) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL2405182 0.97 LMNA (0.95) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL10968452 0.97 LMNA (0.95) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL22471518 0.97 LMNA (0.95) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL11044641 0.97 LMNA (0.95) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL11180245 0.95 LMNA (0.91) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL11180862 0.95 LMNA (0.91) LMNAHTTSLC2A1KDM4ETDP1
Dipyrithione SCHEMBL11182588 0.95 LMNA (0.91) LMNAHTTSLC2A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10065 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 US claimed
US-12336537-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2025-06-24 US claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
US-20250098677-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 US claimed
US-4307089-A ANTIDANDRUFF, FUNGICIDES BACTERICIDES REWO CHEMISCHE WERKE GMBH (DE) 1981-12-22 US claimed
EP-0014268-B1 PROCESS FOR PREPARING BIS-2-PYRIDYL-DISULFIDES RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1981-10-07 EP claimed
US-4288543-A SAMPLING IN LIQUID PHASE WITH ANTIGROWTH AGENTS-BIOLOGICAL PFIZER INC. (US) 1981-09-08 US claimed
US-4256892-A OXIDATION OF THE 2-MERCAPTOPYRIDINE WITH ALKAI OR ALKALINE EARTH CHLORITE RUTGERSWERKE AKTIENGESELLSCHAFT (DE) 1981-03-17 US claimed
US-4163783-A ACID AND A BIS/2-PYRIDYL-1-OXIDE/DISULFIDE KLEIN ROBERT W 1979-08-07 US claimed
US-4161526-A Zinc salt prevention or removal of discoloration in pyrithione, pyrithione salt and dipyrithione compositions STERLING DRUG INC. (US) 1979-07-17 US claimed
US-4152430-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1979-05-01 US claimed
US-4152431-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1979-05-01 US claimed
US-4137311-A CORTICOSTEROIDS, METAL ADDUCTS OF BIS(2-PYRIDYL-1-OXIDE)-DISULFIDE; DERMATITIS, ANTIINFLAMMATORY WILLIAM H. RORER, INC. (US) 1979-01-30 US claimed
US-3954781-A BY REACTING 2-MERCAPTOPYRIDINE-1-OXIDE WITH IN SITU GENERATED HYPOCHLOROUS ACID OLIN CORPORATION (US) 1976-05-04 US claimed