Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.95 |
| ▸ | HTT | P42858 | 2/20 | 0.95 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyrithione SCHEMBL11186942 | 0.98 | LMNA (0.91) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL29364114 | 0.97 | LMNA (1.00) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL21165 | 0.97 | LMNA (1.00) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL11172937 | 0.95 | LMNA (0.86) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL22471518 | 0.95 | LMNA (0.95) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL10973086 | 0.95 | LMNA (0.95) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL11044641 | 0.95 | LMNA (0.95) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL6034282 | 0.95 | LMNA (0.95) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL10968452 | 0.95 | LMNA (0.95) | LMNAHTTSLC2A1KDM4ETDP1 | |
| Dipyrithione SCHEMBL11171931 | 0.93 | LMNA (0.83) | LMNAHTTSLC2A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079679-B1 | METHOD OF TREATMENT OF ALOPECIA WITH MONOTERPENOIDS | CELLMID LTD (AU) | 2019-08-14 | — | — | EP | disclosed |
| US-20180360792-A1 | Method of Treatment of Alopecia with Monoterpenoids | Cellmid Limited (AU) | 2018-12-20 | — | — | US | disclosed |
| EP-2538963-B1 | METHOD OF TREATMENT OR PREVENTION OF HAIR LOSS OR FOR THE ENHANCEMENT OF HAIR GROWTH | ADVANGEN INT PTY LTD (AU) | 2017-05-17 | — | — | EP | disclosed |
| US-9622955-B2 | Method of treatment or prevention of hair loss or for the enhancement of hair growth | ADVANGEN INTERNATIONAL PTY LTD (AU) | 2017-04-18 | — | — | US | disclosed |
| US-20160374979-A1 | Method of Treatment of Alopecia with Monoterpenoids | Cellmid Limited (AU) | 2016-12-29 | — | — | US | disclosed |
| EP-3079679-A1 | METHOD OF TREATMENT OF ALOPECIA WITH MONOTERPENOIDS | Cellmid Limited (AU) | 2016-10-19 | — | — | EP | disclosed |
| WO-2016058057-A1 | IMPROVED COSMETIC AND PERSONAL CARE PRODUCTS FROM LEGUMES | BLUE RIBBON ROASTING PTY LTD (AU) | 2016-04-21 | — | — | WO | disclosed |
| CN-103153277-B | Polymer and compositions | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| WO-2015085373-A1 | METHOD OF TREATMENT OF ALOPECIA WITH MONOTERPENOIDS | Cellmid Limited (AU) | 2015-06-18 | — | — | WO | disclosed |
| US-20150044139-A1 | Method of Treatment or Prevention of Hair Loss or for the Enhancement of Hair Growth | ADVANGEN INTERNATIONAL PTY LTD (AU) | 2015-02-12 | — | — | US | disclosed |
| CN-103153277-A | Polymers and compositions | LUBRIZOL ADVANCED MAT INC | 2013-06-12 | — | — | CN | disclosed |
| US-20130067604-A1 | Method of Treatment or Prevention of Hair Loss or for the Enhancement of Hair Growth | ADVANGEN INTERNATIONAL PTY LTD (AU) | 2013-03-14 | — | — | US | disclosed |
| EP-2538963-A1 | METHOD OF TREATMENT OR PREVENTION OF HAIR LOSS OR FOR THE ENHANCEMENT OF HAIR GROWTH | Advangen International Pty Ltd (AU) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011103624-A1 | METHOD OF TREATMENT OR PREVENTION OF HAIR LOSS OR FOR THE ENHANCEMENT OF HAIR GROWTH | ADVANGEN INTERNATIONAL PTY LTD (AU) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160374979-A1 | Method of Treatment of Alopecia with Monoterpenoids | FGF1, FGF2, FGFR1 | LMNA 3388/4885HTT 4216/4885SLC2A1 4762/4885 |
| US-20180360792-A1 | Method of Treatment of Alopecia with Monoterpenoids | FGF1, FGF2, FGFR1 | LMNA 3444/4885HTT 4301/4885SLC2A1 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.