Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 16/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 16/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459203 | 0.84 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL12533585 | 0.79 | RAB9A (0.58) | CYP11B1CYP11B2CYP3A4MAPK1 | |
| SCHEMBL2718952 | 0.78 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL13658677 | 0.77 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL18525554 | 0.77 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL13658668 | 0.76 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL14355101 | 0.75 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP3A4MAPK1 | |
| SCHEMBL14355099 | 0.75 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP3A4CYP2A6 | |
| SCHEMBL12880434 | 0.75 | MAPK1 (0.48) | CYP3A4MAPK1GRM5CYP2A6 | |
| SCHEMBL18459206 | 0.75 | CYP11B1 (0.60) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275357-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-05 | — | — | WO | disclosed |
| EP-4112631-A1 | CASPASE-2 INHIBITOR COMPOUNDS | Kintsugi Therapeutics S.L. (ES) | 2023-01-04 | — | — | EP | disclosed |
| US-10355284-B2 | Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-07-16 | — | — | US | disclosed |