SCHEMBL13658677

SCHEMBL13658677

Cc1c2ccccc2c(C)c2cc(Cc3ccc(-c4ccncc4)nc3)ccc12

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 17/20 0.59
CYP11B2 P19099 17/20 0.59
CYP3A4 P08684 1/20 0.53
WNT3A P56704 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13658668 0.86 CYP11B1 (0.58) CYP11B1CYP11B2CYP3A4WNT3A
SCHEMBL13658680 0.78 PDE10A (0.46) CYP11B1CYP11B2CYP3A4
SCHEMBL21165038 0.77 CYP11B1 (0.64) CYP11B1CYP11B2CYP3A4
SCHEMBL2718952 0.75 CYP11B1 (1.00) CYP11B1CYP11B2CYP3A4
SCHEMBL13658679 0.73 CYP11B1 (0.55) CYP11B1CYP11B2CYP3A4
SCHEMBL12533585 0.70 RAB9A (0.58) CYP11B1CYP11B2CYP3A4
SCHEMBL2716882 0.70 CYP11B1 (1.00) CYP11B1CYP11B2CYP3A4
SCHEMBL2715045 0.69 CYP11B1 (1.00) CYP11B1CYP11B2CYP3A4WNT3A
SCHEMBL20122190 0.68 CYP11B1 (0.80) CYP11B1CYP11B2CYP3A4
SCHEMBL15453682 0.68 CYP11B1 (0.44) CYP11B1CYP11B2CYP3A4WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296695-B2 Bipyridine-based compound and organic light emitting diode employing organic layer comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-29 US disclosed
US-20090256473-A1 BIPYRIDINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DIODE EMPLOYING ORGANIC LAYER COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2009-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090256473-A1 BIPYRIDINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DIODE EMPLOYING ORGANIC LAYER COMPRISING THE SAME OCIAD2, OCIAD1, DRD2 CYP11B1 1697/4885CYP11B2 1226/4885CYP3A4 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.