Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PLEC | Q15149 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20362560 | 0.96 | ABCB1 (0.40) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL12324196 | 0.88 | ABCB1 (0.44) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL20281372 | 0.88 | ABCB1 (0.40) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL13043465 | 0.86 | ABCB1 (0.46) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL26505092 | 0.86 | ABCB1 (0.30) | ABCB1P2RY6 | |
| SCHEMBL19846795 | 0.85 | ABCB1 (0.53) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL19635154 | 0.83 | ABCB1 (0.33) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL21648602 | 0.83 | AR (0.35) | ABCB1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL21165046 | 0.83 | USP2 (0.35) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL26505087 | 0.83 | ABCB1 (0.30) | ABCB1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787946-B2 | Deuterated fluorophores | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787946-B2 | Deuterated fluorophores | HDHD5, DRD4, ARF4 | ABCB1 1409/4885USP2 2609/4885ATM 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.