Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22831333 | 0.89 | MAPT (0.41) | ALDH1A1HTR7MAPTHRH3KEAP1 | |
| SCHEMBL17779820 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HTR7MAPTHRH3KEAP1 | |
| SCHEMBL17779821 | 0.78 | ALDH1A1 (0.35) | ALDH1A1HTR7MAPTHRH3KEAP1 | |
| SCHEMBL2455095 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HTR7MAPTHRH3KEAP1 | |
| SCHEMBL22831368 | 0.76 | SLC6A2 (0.36) | HTR1BCHRNB2CHRNA4DRD2ACHE | |
| SCHEMBL21165370 | 0.74 | HSD17B10 (0.34) | KDM4E | |
| SCHEMBL3763099 | 0.71 | HSD17B10 (0.41) | ALDH1A1MAPTKDM4EACHE | |
| SCHEMBL19445296 | 0.70 | HSD17B10 (0.31) | — | |
| SCHEMBL7618492 | 0.68 | ALDH1A1 (0.81) | ALDH1A1HTR7MAPTHTR1BCHRNB2 | |
| SCHEMBL182607 | 0.68 | HSD17B10 (0.40) | ALDH1A1KDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351669-B2 | Amino derivatives of perfluoropolyethers | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2019-07-16 | — | — | US | disclosed |