Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GSR | P00390 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804818 | 0.96 | ALDH1A1 (0.49) | ALDH1A1TSHRGSRLMNAGAA | |
| SCHEMBL24520448 | 0.85 | HIF1A (0.43) | ALDH1A1TSHRGSRLMNAGAA | |
| SCHEMBL39559 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TSHRGSRLMNAGAA | |
| SCHEMBL2467528 | 0.84 | GSR (0.63) | TSHRGSRLMNAGAAMAPK1 | |
| SCHEMBL1121537 | 0.82 | GSR (0.61) | TSHRGSRLMNAGAAMAPK1 | |
| SCHEMBL526641 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRGSRLMNAGAA | |
| SCHEMBL19488913 | 0.82 | HSPA5 (0.59) | ALDH1A1TSHRGSRLMNAGAA | |
| SCHEMBL2679783 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRGSRLMNAGAA | |
| SCHEMBL11408652 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRGSRLMNAGAA | |
| SCHEMBL9180511 | 0.81 | GABRA1 (0.50) | ALDH1A1TSHRGSRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351771-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-07-16 | — | — | US | disclosed |