SCHEMBL21165796

SCHEMBL21165796

CCOc1ccc(C#Cc2ccccc2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2D6 P10635 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTGDR2 Q9Y5Y4 2/20 0.40
APP P05067 1/20 0.39
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNA4 P43681 1/20 0.38
FFAR1 O14842 3/20 0.38
FFAR4 Q5NUL3 1/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509326 0.86 AR (0.37) L3MBTL1CYP1A2CYP2C19CYP2D6TDP1
SCHEMBL9508737 0.84 CYP2A6 (0.37) FFAR1
SCHEMBL16692008 0.83 TACR2 (0.37) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL9512496 0.83 AAK1 (0.38) L3MBTL1CYP1A2CYP2C19CYP2D6TDP1
SCHEMBL7910413 0.82 ACACB (0.40) FFAR1
SCHEMBL9509292 0.82 RXRA (0.35)
SCHEMBL9508771 0.80 ACACB (0.39) FFAR1FFAR4HSD17B10
SCHEMBL9511465 0.80 ACACB (0.39) L3MBTL1FFAR1FFAR4MAPTHSD17B10
SCHEMBL9355648 0.80 MAPT (0.50) L3MBTL1CYP1A2CYP2C19CYP2D6TDP1
SCHEMBL17975080 0.80 PTGDR2 (0.47) L3MBTL1CYP1A2CYP2C19CYP2D6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190219856-A1 LIQUID CRYSTAL PANEL, SWITCHABLE MIRROR PANEL AND SWITCHABLE MIRROR DISPLAY SHARP KABUSHIKI KAISHA (JP) 2019-07-18 US disclosed