⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707562 | 0.74 | — | — | |
| SCHEMBL9710760 | 0.63 | ALDH1A1 (0.45) | — | |
| SCHEMBL9710754 | 0.63 | ALDH1A1 (0.45) | — | |
| SCHEMBL10050362 | 0.60 | TDP1 (0.33) | — | |
| SCHEMBL26257161 | 0.60 | — | — | |
| SCHEMBL4477801 | 0.60 | — | — | |
| SCHEMBL8546596 | 0.58 | — | — | |
| SCHEMBL14667465 | 0.58 | — | — | |
| SCHEMBL23183408 | 0.57 | — | — | |
| Methylsulfanylmethane SCHEMBL27673289 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | CADENT THERAPEUTICS, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | NOVARTIS AG (CH) | 2019-07-18 | — | — | US | disclosed |