SCHEMBL21166944

SCHEMBL21166944

CC(C)N[C@@H](CCCN)C(=O)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.34
CPB2 Q96IY4 5/20 0.33
GABRR1 P24046 2/20 0.33
SIRT6 Q8N6T7 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
GSR P00390 1/20 0.31
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
NMT2 O60551 1/20 0.31
NMT1 P30419 1/20 0.31
PAOX Q6QHF9 2/20 0.31
RNPEP Q9H4A4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25462341 1.00 FOLH1 (0.34) FOLH1CPB2GABRR1SIRT6SIRT1
SCHEMBL13254054 1.00 FOLH1 (0.34) FOLH1CPB2GABRR1SIRT6SIRT1
SCHEMBL7604714 0.94 FOLH1 (0.40) FOLH1CPB2SIRT6SIRT1GSR
SCHEMBL27250343 0.94 FOLH1 (0.40) FOLH1CPB2SIRT6SIRT1GSR
SCHEMBL13573523 0.94 FOLH1 (0.40) FOLH1CPB2SIRT6SIRT1GSR
SCHEMBL12762368 0.88 GABRR1 (0.40) GABRR1DPP7
SCHEMBL21166946 0.88 GABRR1 (0.40) GABRR1DPP7
SCHEMBL23191801 0.87 NMT1 (0.40) FOLH1CPB2SIRT6SIRT1DPP4
SCHEMBL21399748 0.86 SIRT6 (0.36) FOLH1CPB2GABRR1SIRT6SIRT1
SCHEMBL23330464 0.86 FOLH1 (0.35) FOLH1CPB2GABRR1SIRT6SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767354-B2 Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors JANSSEN PHARMACEUTICA NV (BE) 2023-09-26 US disclosed
US-20230151074-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-05-18 US disclosed
US-20210163566-A1 Antibody-Coupled Cyclic Peptide Tyrosine Tyrosine Compounds as Modulators of Neuropeptide Y Receptors JANSSEN PHARMACEUTICA NV (BE) 2021-06-03 US disclosed
US-10793601-B2 Therapeutic spalt-like transcription factor 4 (SALL4) peptide NATIONAL UNIVERSITY OF SINGAPORE (SG) 2020-10-06 US disclosed
US-20190218253-A1 Therapeutic SALL4 Peptide AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218253-A1 Therapeutic SALL4 Peptide RBBP4, RBBP5, RB1 FOLH1 2640/4885CPB2 1912/4885GABRR1 1991/4885
US-10793601-B2 Therapeutic spalt-like transcription factor 4 (SALL4) peptide RBBP4, SALL4, RBBP5 FOLH1 2155/4885CPB2 2463/4885GABRR1 1629/4885
US-20210163566-A1 Antibody-Coupled Cyclic Peptide Tyrosine Tyrosine Compounds as Modulators of Neuropeptide Y Receptors NPY1R, NPY5R, NPY2R FOLH1 911/4885CPB2 1246/4885GABRR1 230/4885
US-11767354-B2 Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors NPY1R, NPY5R, NPY2R FOLH1 911/4885CPB2 1246/4885GABRR1 230/4885
US-20230151074-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR FOLH1 2850/4885CPB2 3557/4885GABRR1 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.