SCHEMBL21166972

SCHEMBL21166972

Cn1c2cc(-c3c(F)cc(F)cc3F)ccc2c(=O)c2cc3c(cc21)c(=O)c1ccc(-c2c(F)cc(F)cc2F)cc1n3C

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.51
PKM P14618 1/20 0.44
L3MBTL1 Q9Y468 7/20 0.42
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
RXFP1 Q9HBX9 3/20 0.40
POLB P06746 2/20 0.40
GAA P10253 1/20 0.40
MAPK14 Q16539 1/20 0.39
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
TLR9 Q9NR96 1/20 0.35
HCRTR1 O43613 2/20 0.34
TNKS2 Q9H2K2 1/20 0.34
MAOB P27338 1/20 0.34
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987309 0.92 ATM (0.49) ATMPKML3MBTL1NPC1RAB9A
SCHEMBL20987304 0.80 ATM (0.49) ATMPKML3MBTL1NPC1RAB9A
SCHEMBL86061 0.79 ATM (0.77) ATMPKML3MBTL1NPC1RAB9A
SCHEMBL20987491 0.75 PIM1 (0.42) NPC1RXFP1
SCHEMBL13925420 0.75 ATM (0.67) ATML3MBTL1NPC1RAB9AGAA
SCHEMBL21167110 0.74 MAOB (0.57) ATMPKML3MBTL1NPC1RAB9A
SCHEMBL21023473 0.72 ATM (0.44) ATMPKML3MBTL1GAAMEN1
SCHEMBL19055418 0.72 L3MBTL1 (0.64) ATMPKML3MBTL1NPC1RAB9A
SCHEMBL4408008 0.72 ATM (0.67) ATMPKML3MBTL1NPC1RAB9A
SCHEMBL20987308 0.72 ATM (0.50) ATMPKML3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221745-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed