SCHEMBL20987308

SCHEMBL20987308

Cn1c2ccc(-c3ccccc3F)cc2c(=O)c2cc3c(cc21)c(=O)c1cc(-c2ccccc2F)ccc1n3C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
TNKS O95271 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48
PTPRC P08575 1/20 0.46
PTPN1 P18031 1/20 0.46
PGR P06401 1/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
PKM P14618 1/20 0.43
ICMT O60725 1/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KMO O15229 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
MAP4K4 O95819 1/20 0.40
ACMSD Q8TDX5 1/20 0.39
HCRTR1 O43613 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987304 0.85 ATM (0.49) ATML3MBTL1PKMNPC1RAB9A
SCHEMBL20987496 0.82 TNKS2 (0.48) ATMTNKS2PGRL3MBTL1NPC1
SCHEMBL20987303 0.82 TRPA1 (0.52) ATMPGRMEN1KMT2AHSD17B10
SCHEMBL20987498 0.81 ATM (0.46) ATML3MBTL1PKMNPC1RAB9A
SCHEMBL20987318 0.80 MAOB (0.50) ATML3MBTL1PKMNPC1RAB9A
SCHEMBL21167125 0.79 ATM (0.40) ATMTNKSTNKS2PTPRCPTPN1
SCHEMBL20987540 0.79 ATM (0.50) ATML3MBTL1PKMNPC1RAB9A
SCHEMBL20987309 0.79 ATM (0.49) ATML3MBTL1PKMNPC1RAB9A
SCHEMBL20987549 0.78 ATM (0.46) ATML3MBTL1PKMNPC1RAB9A
SCHEMBL21023341 0.77 ATM (0.47) ATMTNKSTNKS2L3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190140189-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190140189-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND CRY1, CDH1, TEAD1 ATM 2642/4885TNKS 1821/4885TNKS2 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.