SCHEMBL21166973

SCHEMBL21166973

Cc1cccc2c(=O)c3cc4c(cc3n(C)c12)c(=O)c1ccc(-c2ccccc2)cc1n4C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.52
L3MBTL1 Q9Y468 4/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
ALKBH5 Q6P6C2 1/20 0.47
FTO Q9C0B1 1/20 0.47
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
LIMK1 P53667 2/20 0.46
ATM Q13315 1/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
PKM P14618 1/20 0.44
MAOA P21397 1/20 0.43
TNKS2 Q9H2K2 1/20 0.42
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TLR9 Q9NR96 1/20 0.39
PIM1 P11309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21166969 0.87 MAOB (0.52) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL21023170 0.86 ALKBH5 (0.63) L3MBTL1NPC1RAB9AALKBH5FTO
SCHEMBL21167110 0.86 MAOB (0.57) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL21166970 0.85 L3MBTL1 (0.63) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL20987444 0.79 ATM (0.56) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL25757985 0.79 ALKBH5 (0.73) NPC1RAB9AALKBH5FTOGAA
SCHEMBL21023320 0.77 HSD17B10 (0.52) L3MBTL1NPC1RAB9APOLBGAA
SCHEMBL20987318 0.77 MAOB (0.50) MAOBL3MBTL1NPC1RAB9APOLB
SCHEMBL18160217 0.76 ALKBH5 (0.65) MAOBL3MBTL1NPC1RAB9AALKBH5
SCHEMBL21023175 0.76 HSD17B10 (0.50) MAOBL3MBTL1NPC1RAB9ALIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221745-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed