⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3283129 | 0.77 | — | — | |
| SCHEMBL14963882 | 0.72 | RRM1 (0.36) | — | |
| SCHEMBL4780554 | 0.71 | KMT2A (0.53) | — | |
| SCHEMBL6868957 | 0.70 | — | — | |
| SCHEMBL9403919 | 0.70 | MAOA (0.53) | — | |
| SCHEMBL30335428 | 0.69 | GAA (0.44) | — | |
| SCHEMBL7379202 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL10683006 | 0.69 | — | — | |
| SCHEMBL12126849 | 0.68 | — | — | |
| SCHEMBL19520155 | 0.67 | HRH4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |