Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 11/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 10/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.36 |
| ▸ | CSF1R | P07333 | 4/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23127929 | 0.81 | CSF1R (0.53) | FGFR3FGFR2FGFR1CSF1RMET | |
| SCHEMBL24591047 | 0.77 | CSF1R (0.37) | FGFR3FGFR2FGFR1CSF1RMET | |
| SCHEMBL24590984 | 0.76 | MET (0.56) | FGFR3FGFR2FGFR1CSF1RMET | |
| SCHEMBL16882482 | 0.73 | MET (0.42) | FGFR3FGFR2FGFR1METKDR | |
| SCHEMBL12487155 | 0.73 | MET (0.66) | MET | |
| SCHEMBL21167449 | 0.72 | MET (0.41) | FGFR3FGFR2FGFR1METKDR | |
| SCHEMBL23191356 | 0.72 | MET (0.47) | FGFR3METKDR | |
| SCHEMBL22475813 | 0.71 | CSF1R (0.42) | FGFR3FGFR2FGFR1CSF1RMET | |
| SCHEMBL23128045 | 0.70 | CSF1R (0.42) | FGFR3FGFR2FGFR1CSF1RKDR | |
| SCHEMBL22475798 | 0.70 | CSF1R (0.40) | FGFR3FGFR2FGFR1CSF1RATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |