Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20519517 | 0.84 | MET (0.44) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL8297005 | 0.84 | MET (0.44) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL15508809 | 0.84 | MET (0.44) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL299606 | 0.84 | MET (0.44) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL2631762 | 0.82 | MET (0.45) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL20247028 | 0.81 | MET (0.43) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL8296605 | 0.80 | MEN1 (0.53) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL29229697 | 0.80 | MET (0.41) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL15508810 | 0.79 | L3MBTL1 (0.47) | METKDM4CL3MBTL1NPC1RAB9A | |
| SCHEMBL15659168 | 0.78 | MET (0.53) | METKDM4CL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795573-B1 | CERTAIN TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | HUTCHISON MEDIPHARMA LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |