SCHEMBL2116744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2990425	0.85	SLC6A4 (0.43)	SLC6A4HTR2AMEN1ALDH1A1POLB
	SCHEMBL8709749	0.81	CSNK2A1 (0.41)	MEN1ALDH1A1KMT2AXDHSMN1; SMN2
	SCHEMBL1052715	0.81	KDM4E (0.31)	ALDH1A1XDHKDM4EHTT
	SCHEMBL6911481	0.80	CYP1A2 (0.39)	SLC6A4HTR2AALDH1A1HPGDKCNH2
	SCHEMBL2116117	0.79	MAPK1 (0.41)	SLC6A4HTR2AMEN1ALDH1A1POLB
	SCHEMBL8681344	0.79	ALDH1A1 (0.38)	SLC6A4HTR2AMEN1ALDH1A1POLB
	SCHEMBL28867665	0.78	XDH (0.51)	ALDH1A1HPGDXDHUSP2KDM4E
	SCHEMBL29940793	0.78	XDH (0.51)	ALDH1A1HPGDXDHUSP2KDM4E
	SCHEMBL6884931	0.77	MAPT (0.48)	HTR2AMEN1ALDH1A1HPGDKMT2A
	SCHEMBL27920637	0.77	HDAC3 (0.40)	SLC6A4HTR2AALDH1A1KCNH2NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.