Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 9/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475692 | 0.83 | HDAC3 (0.36) | HDAC3ACACBUSP30PDK1MET | |
| SCHEMBL21167485 | 0.83 | HDAC3 (0.36) | HDAC3 | |
| SCHEMBL21171413 | 0.83 | HDAC3 (0.33) | HDAC3USP30PDK1 | |
| SCHEMBL21167505 | 0.77 | HDAC3 (0.36) | HDAC3FCER2ACACBUSP30PDK1 | |
| SCHEMBL22754434 | 0.74 | MET (0.45) | HDAC3MET | |
| SCHEMBL21167680 | 0.73 | HDAC3 (0.40) | HDAC3ACACBUSP30PDK1MET | |
| SCHEMBL21167434 | 0.72 | HDAC3 (0.38) | HDAC3MET | |
| SCHEMBL22475855 | 0.71 | HDAC3 (0.37) | HDAC3ACACB | |
| SCHEMBL22475886 | 0.71 | HDAC3 (0.37) | HDAC3 | |
| SCHEMBL22475862 | 0.70 | HDAC3 (0.36) | HDAC3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |