Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 7/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21167505 | 0.86 | HDAC3 (0.36) | HDAC3ACACBUSP30METANO1 | |
| SCHEMBL22475936 | 0.83 | KDR (0.42) | HDAC3METKDR | |
| SCHEMBL21167679 | 0.82 | HDAC3 (0.46) | HDAC3ACACBUSP30ANO1MEN1 | |
| SCHEMBL22475692 | 0.75 | HDAC3 (0.36) | HDAC3ACACBUSP30METPDK1 | |
| SCHEMBL21167813 | 0.73 | KDR (0.39) | HDAC3ANO1KDR | |
| SCHEMBL21167486 | 0.73 | HDAC3 (0.35) | HDAC3ACACBUSP30METPDK1 | |
| SCHEMBL21167820 | 0.70 | KDR (0.39) | HDAC3KDR | |
| SCHEMBL24591110 | 0.70 | KDR (0.39) | HDAC3KDR | |
| SCHEMBL21171413 | 0.69 | HDAC3 (0.33) | HDAC3USP30PDK1 | |
| SCHEMBL22754434 | 0.68 | MET (0.45) | HDAC3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795573-B1 | CERTAIN TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | HUTCHISON MEDIPHARMA LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |